Royal Jelly for Arthritis

Angela, CNP

Arthritis sufferers are going to be very excited about this. Recently a group of researchers got together to develop a potential medicine for rheumatoid arthritis. They choose to study a compound in royal jelly called 10-hydroxy-2-decenoic acid. We'll just call it 10H2DA for short though since it is a such a mouthful to pronounce.

I won't bore you with the scientific details, but what the researchers found was that the 10H2DA blocked two pro-inflammatory signaling pathways in their study. What does this mean for you?

When a disease state exists in your cells such as arthritis, your cells send signals that there is an issue (the disease) and that in order to protect itself, inflammatory chemicals need to be brought to the scene (your joint) to help heal the area.   It is your body's biological response to try and 'remove' the disease or damaged cells.   Initially, this is highly beneficial but sometimes inflammation can cause further inflammation, leading to chronic inflammation which is often the case with Rheumatoid Arthritis.  RA is an autoimmune response whereby the immune system attacks healthy tissue, mistaking it for harmful pathogens.

According to this study, Royal Jelly might be helpful in a condition such as RA because it interrupts these signals continually asking for more inflammation, which over the long term leads to damage of the joint, pain and disability. 

These scientists concluded that 10H2DA (the royal jelly compound) may be of potential therapeutic value in inhibiting joint destruction in rheumatoid arthritis.

If you'd like to read the entire study, it can be found in the Journal of Ethnopharmacol, 2010 Feb 3. 

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